Prognostic factors in glioblastoma multiforme
نویسندگان
چکیده
منابع مشابه
Survival and prognostic factors of patients with unresectable glioblastoma multiforme.
The aim of this study was to assess survival and prognostic factors of 98 consecutive patients with unresectable glioblastoma multiforme (GBM) after stereotactic biopsy. Patients were diagnosed between 1993 and 1998, and the treatment modality subsequent to stereotactic biopsy was determined by the year of diagnosis. Before 1995, patients did not receive further specific therapy after stereotac...
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Malignant glioblastoma multiform (GBM, WHO grade IV) are the most malignant and prevalent intracranial tumor providing for well over one half of all gliomas (Hoffman et al., 2006; Schneider et al., 2010). GBM is characterized by a rapid growth and short time to progression in most treated patients. Current therapeutic modalities include surgical resection, radio-surgical or external irradiation...
متن کاملPrognostic factors influencing clinical outcomes of glioblastoma multiforme.
BACKGROUND Glioblastoma multiforme (GBM) is the most malignant kind of astrocytic tumors and is associated with a poor prognosis. In this retrospective study, we assessed the clinical, radiological, genetic molecular and treatment factors that influence clinical outcomes of patients with GBM. METHODS A total of 116 patients with GBM who received surgery and radiation between January 2006 and ...
متن کاملGlioblastoma Multiforme in Children, A Case-Report
ABSTRACT: Glioblastoma multiforme is the most malignant primary brain tumor .It usually occurs in the 5th and 6th decades of life and is rare in childern. In this paper a case of glioblastoma multiforme is reported in a ten year - old child who presented with two week's history of headache with no neurological defect.C.T scan revealed å right frontal mass with massive surrounding oedema. He w...
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Patients with primary glioblastoma multiforme (GBM) have one of the lowest overall survival rates among cancer patients, and reliable biomarkers are necessary to predict patient outcome. Cytochrome c oxidase (CcO) promotes the switch from glycolytic to OXPHOS metabolism, and increased CcO activity in tumors has been associated with tumor progression after chemotherapy failure. Thus, we investig...
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ژورنال
عنوان ژورنال: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery
سال: 2010
ISSN: 0103-5355,2359-5922
DOI: 10.1055/s-0038-1625613